EXTENDED REPORT Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment

نویسندگان

  • Juergen Rech
  • Axel J Hueber
  • Stephanie Finzel
  • Matthias Englbrecht
  • Judith Haschka
  • Bernhard Manger
  • Arnd Kleyer
  • Michaela Reiser
  • Jayme Fogagnolo Cobra
  • Camille Figueiredo
  • Hans-Peter Tony
  • Stefan Kleinert
  • Joerg Wendler
  • Florian Schuch
  • Monika Ronneberger
  • Martin Feuchtenberger
  • Martin Fleck
  • Karin Manger
  • Wolfgang Ochs
  • Matthias Schmitt-Haendle
  • Hanns-Martin Lorenz
  • Hubert Nuesslein
  • Rieke Alten
  • Joerg Henes
  • Klaus Krueger
  • Georg Schett
  • Tore K Kvien
چکیده

Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment Juergen Rech, Axel J Hueber, Stephanie Finzel, Matthias Englbrecht, Judith Haschka, Bernhard Manger, Arnd Kleyer, Michaela Reiser, Jayme Fogagnolo Cobra, Camille Figueiredo, Hans-Peter Tony, Stefan Kleinert, Joerg Wendler, Florian Schuch, Monika Ronneberger, Martin Feuchtenberger, Martin Fleck, Karin Manger, Wolfgang Ochs, Matthias Schmitt-Haendle, Hanns-Martin Lorenz, Hubert Nuesslein, Rieke Alten, Joerg Henes, Klaus Krueger, Georg Schett

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Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment

OBJECTIVE To analyse the role of multibiomarker disease activity (MBDA) score in predicting disease relapses in patients with rheumatoid arthritis (RA) in sustained remission who tapered disease modifying antirheumatic drug (DMARD) therapy in RETRO, a prospective randomised controlled trial. METHODS MBDA scores (scale 1-100) were determined based on 12 inflammation markers in baseline serum s...

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تاریخ انتشار 2015